M. Modaresi; M. Messripour; R. Rajaei
Abstract
Cinnamon is a plant with scientific name Cinnamomum zeylanicum Nees which belongs to Lauraceae family. This plant has many pharmaceutical effects and one of the most important ones is increasing sexuality. This research considered the effects of Cinnamon bark extract on structure of testis tissue and ...
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Cinnamon is a plant with scientific name Cinnamomum zeylanicum Nees which belongs to Lauraceae family. This plant has many pharmaceutical effects and one of the most important ones is increasing sexuality. This research considered the effects of Cinnamon bark extract on structure of testis tissue and number of sexual cells in Balb/c mice. First, samples separated randomly to six groups (four treatment groups and two groups as control and placebo), each group contained eight samples in a same condition. Cinnamon hydro-ethanol extract provided in different dose (50,100, 200 and 400mg/kg/2day) and injected intraperitonealy for 20 days to treatment groups and also used normal saline and ethanol for injecting to placebo group (Zero dose). The most important parameters evaluated in this research included: the testicles weight changes, probably histological changes in testis and change in number of sexual cells compared to control group. The number of primary spermatocytes and assess of histological properties were done with provided sections of seminiferous tubules using light microscope. Also, the spermatozoids were counted using hemocytometer lamel. The analysis of results indicated that no significant differences were observed in weight of testicles and histological properties in any group. The number of primary spermatocytes and spermatozoids could be increased significantly in dose of 100, 200 and 400mg/kg/2day compared to other groups. Results indicated positive effect of cinnamon extract on male reproductive system because number of sexual cells increased significantly.
M. Modaresi; M. Messripoor; M. Asadi Morghmaleki; M.K. Hamadanian
Volume 24, Issue 2 , August 2008, , Pages 237-243
Abstract
It is desirable to use of point out to herbal components to avoid undesirable effects of chemical drugs. Saffron is used widespread as food colorant, flavor and reputes in folk medicine as a drug. Recent studies have revealed that components of saffron may have a number of physiological effects on different ...
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It is desirable to use of point out to herbal components to avoid undesirable effects of chemical drugs. Saffron is used widespread as food colorant, flavor and reputes in folk medicine as a drug. Recent studies have revealed that components of saffron may have a number of physiological effects on different organs of body. The aim of the present study was to clarify the efficacy of saffron on the histological properties of testis in mice. Four groups, including eight adult male Balb/C mice weighing 305g were used in this study. Saffron extract in doses of 25, 50 and 100 were injected intraperitoneally for 20 days to the experimental groups. Control group received normal saline as placebo. Histological properties as seminiferous tubules scattering, testis weight and the number of primary spermatocytes, were compared with the placebo controlled group. The number of primary spermatocytes increased significantly compared to with placebo but no significant differences were observed in histological properties and testis weight between experimental groups and placebo controlled group. The results of this study indicate that saffron extract can modify the reproduction activities in male mice.
